Eleonora Aronica Selected Research

Malformations of Cortical Development

1/2022	The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission.
10/2021	Impaired myelin production due to an intrinsic failure of oligodendrocytes in mTORpathies.
1/2021	Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE).
1/2020	Tuberous Sclerosis Complex as Disease Model for Investigating mTOR-Related Gliopathy During Epileptogenesis.
1/2018	Contribution of Altered Endocannabinoid System to Overactive mTORC1 Signaling in Focal Cortical Dysplasia.
11/2017	Impaired oligodendroglial turnover is associated with myelin pathology in focal cortical dysplasia and tuberous sclerosis complex.
1/2014	Cell injury and premature neurodegeneration in focal malformations of cortical development.
4/2011	Activation of Toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development.
12/2009	Doublecortin-like (DCL) expression in focal cortical dysplasia and cortical tubers.
3/2009	DLG3/SAP102 protein expression in malformations of cortical development: a study of human epileptic cortex by tissue microarray.

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Eleonora Aronica Research Topics

Disease

91	Epilepsy (Aura) 01/2022 - 07/2002
60	Seizures (Absence Seizure) 06/2022 - 07/2002
53	Tuberous Sclerosis (Bourneville's Disease) 11/2022 - 10/2004
36	Temporal Lobe Epilepsy 10/2021 - 07/2002
31	Focal Cortical Dysplasia 06/2022 - 06/2003
31	Status Epilepticus (Complex Partial Status Epilepticus) 10/2021 - 01/2002
28	Neoplasms (Cancer) 01/2022 - 06/2002
22	Inflammation (Inflammations) 10/2021 - 01/2008
17	Glioma (Gliomas) 10/2021 - 05/2003
17	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2021 - 05/2003
13	Astrocytoma (Pilocytic Astrocytoma) 11/2022 - 01/2011
13	Malformations of Cortical Development 01/2022 - 05/2003
12	Partial Epilepsies (Epilepsy, Partial) 06/2022 - 01/2014
11	Drug Resistant Epilepsy 01/2022 - 09/2003
11	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 10/2006
10	Encephalitis (Encephalitis, Rasmussen) 01/2019 - 05/2003
9	Inborn Genetic Diseases (Disease, Hereditary) 01/2022 - 07/2015
9	Hippocampal Sclerosis 10/2021 - 05/2004
8	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 05/2003
7	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 09/2005
7	Ganglioglioma 01/2021 - 09/2003
7	Brain Diseases (Brain Disorder) 01/2020 - 01/2013
7	Disease Progression 01/2019 - 01/2014
6	Brain Neoplasms (Brain Tumor) 11/2022 - 03/2010
6	Neuroinflammatory Diseases 06/2022 - 11/2018
6	Autism Spectrum Disorder 01/2022 - 01/2016
5	Muscular Diseases (Myopathy) 04/2022 - 03/2015
5	Intellectual Disability (Idiocy) 01/2022 - 03/2016
5	Autistic Disorder (Autism) 01/2020 - 05/2012
5	Hemimegalencephaly 01/2019 - 12/2004
5	Gliosis 01/2016 - 05/2003
4	Myositis (Idiopathic Inflammatory Myopathies) 04/2022 - 03/2015
4	Neurodevelopmental Disorders 10/2021 - 06/2007
4	Brain Injuries (Brain Injury) 09/2021 - 03/2005
3	Dermatomyositis (Dermatopolymyositis) 04/2022 - 03/2015
3	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2019
3	Infections 01/2022 - 04/2008
3	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 01/2022 - 05/2017
3	Epileptic Syndromes 01/2021 - 07/2002
3	Carcinogenesis 01/2020 - 12/2012
3	Breast Neoplasms (Breast Cancer) 01/2020 - 06/2005
3	Medulloblastoma 08/2012 - 08/2006
2	Inclusion Body Myositis 04/2022 - 03/2015
2	Neurologic Manifestations (Neurological Manifestations) 01/2022 - 04/2008
2	Hyperplasia 01/2022 - 01/2021
2	Multiple System Atrophy 01/2022 - 07/2015

Drug/Important Bio-Agent (IBA)

51	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2002
46	trans-sodium crocetinate (crocetin)IBA 11/2022 - 10/2004
31	Pharmaceutical PreparationsIBA 06/2022 - 07/2002
16	TOR Serine-Threonine KinasesIBA 01/2022 - 01/2011
15	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2012
15	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021 - 07/2002
12	Kainic Acid (Kainate)IBA 10/2021 - 07/2002
10	CytokinesIBA 06/2022 - 01/2008
10	Messenger RNA (mRNA)IBA 01/2021 - 07/2002
9	Sirolimus (Rapamycin)FDA Link 11/2022 - 07/2012
8	Mechanistic Target of Rapamycin Complex 1IBA 10/2021 - 01/2013
8	gamma-Aminobutyric Acid (GABA)IBA 03/2021 - 12/2007
7	InterleukinsIBA 01/2022 - 03/2005
7	Biomarkers (Surrogate Marker)IBA 06/2019 - 08/2010
7	Adenosine (Adenocard)FDA LinkGeneric 01/2018 - 09/2009
6	HMGB1 Protein (HMG1)IBA 01/2022 - 04/2010
6	RNA (Ribonucleic Acid)IBA 01/2021 - 10/2006
6	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2020 - 07/2002
5	mitomycin C-dextranIBA 10/2021 - 09/2009
5	AntibodiesIBA 01/2020 - 09/2007
5	EnzymesIBA 01/2020 - 01/2012
5	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 01/2019 - 06/2003
5	Glutamic Acid (Glutamate)FDA Link 06/2014 - 08/2006
4	Toll-Like Receptor 4IBA 01/2022 - 04/2010
4	RNA-Binding Proteins (RNA-Binding Protein)IBA 10/2021 - 09/2013
4	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 03/2021 - 01/2002
4	Vigabatrin FDA Link 01/2021 - 09/2018
4	AlbuminsIBA 11/2020 - 12/2013
4	Amyloid (Amyloid Fibrils)IBA 01/2020 - 07/2013
4	Interleukin-6 (Interleukin 6)IBA 01/2018 - 04/2008
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2016 - 06/2008
3	Ligases (Synthetase)IBA 04/2022 - 03/2015
3	Complement System Proteins (Complement)IBA 01/2022 - 09/2014
3	Everolimus FDA Link 01/2022 - 05/2012
3	AutoantibodiesIBA 12/2021 - 03/2015
3	IronIBA 10/2021 - 09/2005
3	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 07/2018
3	AMPA Receptors (AMPA Receptor)IBA 01/2020 - 06/2009
3	Hematoxylin (Haematoxylon)IBA 01/2020 - 05/2010
3	Eosine Yellowish-(YS) (Eosin)IBA 01/2020 - 05/2010
3	Adenosine KinaseIBA 01/2020 - 07/2011
3	Protein Isoforms (Isoforms)IBA 01/2020 - 07/2004
3	Therapeutic UsesIBA 06/2019 - 01/2016
3	Carrier Proteins (Binding Protein)IBA 01/2019 - 07/2014
3	Toll-Like Receptors (Toll-Like Receptor)IBA 03/2017 - 04/2011
3	ParaffinIBA 09/2014 - 05/2010
3	Receptor for Advanced Glycation End ProductsIBA 10/2013 - 04/2011
3	Phenytoin (Dilantin)FDA LinkGeneric 02/2010 - 07/2002
3	major vault proteinIBA 12/2004 - 09/2003
2	ChloridesIBA 06/2022 - 11/2018
2	Ataxin-3IBA 01/2022 - 05/2017
2	Pyruvate CarboxylaseIBA 10/2021 - 03/2021

Therapy/Procedure

22	Therapeutics 10/2021 - 04/2012
4	Drug Therapy (Chemotherapy) 01/2021 - 09/2011